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About DRG

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Projects & Publications

Our studies focus on developing sensors and diagnostic kits for the use in medical, pharmaceutical and food industries.

Our studies have been supported by The Scientific and Technology Research Council of Turkey (1001 - Scientific and Technological Research Projects Funding Program and 2210-C Scholarship Program)

Research activity of DRG:

Immunoassay

Current research project includes: development the different immunoassay formats (ELISA, TRFIA) based on the interaction between antibody and antigen. Our main aim is to develop diagnostic kits for the use in medical area especially diagnosis of diabetes mellitus.

Sensors

Our research in this area includes sensors for monitoring various clinic parameters and food additives. We are interested in developing nanomaterial based electrochemical sensor and using novel nanoparticles.

Genosensor

The research in this topic focuses on developing sensors based on interaction between DNA and drug for investigation of DNA binding mechanisms of drug molecules. These studies play important role in designing more efficient drugs.

Koyuncu, D., Erden, P.E., Pekyardımcı, Ş. and Kılıç, E. A new amperometric carbon paste electrode for ethanol determination. Analytical Letters, 40, 2007, 1904–1922.

Koyuncu Zeybek, D. Zeybek, B. Özçiçek Pekmez, N. Pekyardımcı, Ş. and Kılıç, E. Development of an Amperometric Enzyme Electrode based on Poly(o-Phenylenediamine) for the Determination of Total Cholesterol in SerumJ. Braz. Chem. Soc., 23, (12) 2012, 2222- 2231.

Aydoğdu, G., Koyuncu Zeybek, D., Zeybek, B. and Pekyardımcı, Ş. Electrochemical sensing of NADH on NiO nanoparticles-modified carbon paste electrode and fabrication of ethanol dehydrogenase-based biosensor. J. Appl. Electrochem. 43, 2013, 523–531.

Aydoğdu, G., Koyuncu Zeybek, D., Pekyardımcı, Ş. And Kılıç, E. A novel amperometric biosensor based on ZnO nanoparticles-modified carbon paste electrode for determination of glucose in human serum. Artificial Cells, Nanomedicine, and Biotechnology 41, (5) 2013, 332-338.

Aydoğdu, G. , Günendi, G., Koyuncu Zeybek, D., Zeybek, B. and Pekyardımcı, Ş. A novel electrochemical DNA biosensor based on poly-(5-amino-2-mercapto-1,3,4-thiadiazole) modified glassy carbon electrode for the determination of nitrofurantoin. Sensors and Actuators B: Chemical. Volume 197, 2014, 211–219.

D.K.Zeybek, B.Demir, B.Zeybek, Ş. Pekyardımcı "A sensitive electrochemical DNA biosensor for antineoplastic drug 5-fluorouracil based on glassy carbon electrode modified with poly(bromocresolpurple)", Talanta, Volume 144, 2015, 793-800.